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The progression of clinical effects goes from anxiolysis to sedation to somnolence to coma

Low-quality products may contain impurities, improper copper binding, or degradation products that cause adverse effects while providing minimal benefit

Black and Hispanic populations appear to have a higher prevalence of ME/CFS with worse severity than other racial groups (9, 14)

Decrease dose if: Experiencing consistent side effects (headaches, fatigue, GI disturbance), achieving satisfactory results at current dose with no need for escalation, or cost considerations favor using minimum effective dose

Procurement managers should ask for packaging that doesn't need to be frozen and thawed too often

In accordance with the methodology acquired by Nolan, et al