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For some with significant obesityrelated risks or chronic metabolic disorders, GLP1 may function as longterm maintenancesimilar to other chronic condition therapies

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This analysis confirmed a significant association between GLP-1 RAs and these NAEs (ROR 1.44, 95% CI 1.411.46), with variation observed across different GLP-1 RAs (Fig

Experimental studies in animals provide additional insight: GLP-1 analogs increased testosterone synthesis and improved sperm mitochondrial integrity in diabetic and obese models

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