This study found that the total harmonic distortion increases in a pure DOPC monolayer, but in a DPPC:DOPC system NPs decrease the overall distortion, leading to a more linear response between area compression and surface pressure [422]
While very high oral doses (1,000 to 2,000 mcg) can achieve some passive absorption without intrinsic factor roughly 1% of the dose is absorbed passively many clinicians prefer the reliability and rapid correction offered by injections in this population
This extra step prevents costly research errors
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As a result, it is often seen as a gentler option
An additional peak of protection was seen at 10 13 M (100 fM) but was inconsistent across experiments, so all additional experiments were run with 10 6 M (1 M) Dihexa