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And we still dont fully understand the long-term effects of chronic GLP-1 use

The result is that familiar wave of heat followed by drenching perspiration

More serious risks can include pancreatitis, gallbladder problems, kidney injury from dehydration, allergic reactions, and worsening diabetic retinopathy in some people

Similarly, cardiovascular benefits independent of GLP-1R activation have also been demonstrated [38]

SSTRs, particularly SSTR2 and SSTR5, are highly expressed on somatotrophs in GH-secreting pituitary tumors, in which SSAs inhibits GH secretion by impeding adenylyl cyclase and decreasing cAMP levels 15,16