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Practical Takeaways GLP-1 receptor agonists may increase kidney stone risk primarily through dehydration and reduced fluid intake, particularly early in treatment
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Sanger sequencing of the cloned gene revealed six mutations in comparison with the published jr PPO1 sequence (FJ769240.1) 15 , five of them were silent and one resulted in the exchange of Val107Ile, which does not influence the enzymatic behavior of jr PPO1 (see supporting information)
Common side effects may include: nausea diarrhea vomiting constipation decreased appetite abdominal pain fatigue Rare, but serious side effects may include: severe gastrointestinal events leading to dehydration and kidney injury pancreatitis (severe abdominal pain) gallbladder disease severe allergic reactions hypoglycemia when used with insulin or a sulfonylurea diabetic retinopathy complications in those with type 2 diabetes It's easy to get started
For 5 mg/mL vials , 100 units would give you 5 mg, which is more than double the maximum FDA-approved weekly dose
30 mg vial + 3.0 mL = 10 mg/mL
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