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The erratic nerve signaling that causes the rapid heart rate and blood pressure swings in POTS is worsened by the lack of antioxidant protection in the central nervous system

While a low incidence of pancreatitis with mild symptoms was also recognized ( This study found that the median time to onset of drug-associated AP was 31 days (IQR 7102 days), with more than 75% of reported cases occurring within the first 100 days after the initiation of drug use

Multiply that by a dozen employees, and your plans pharmacy expense quickly balloons

Hypoglycemia (low blood sugar) can occur, especially when using other diabetic medications concurrently

Muscle pain is occasionally reported, particularly at higher doses

Those results describe a compound studied under defined protocols and monitoring, not a product cleared for public use