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27 , have recently reported that cancer cell lines subject to hypoxia are more invasive, have increased migratory ability and an epithelial-mesenchymal transition (EMT) phenotype 27

PMID 17259171

163 The second pathway involves the transcriptional inhibition of AMPK activators such as Sestrin-1/Sestrin-2 by mutant p53

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That added component is what shifts the blend more clearly toward inflammation-related and barrier-oriented research logic, rather than a repair-only emphasis