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Clinical trials have explored the safety profile of AOD and reported few adverse effects, such as insulin resistance or unwanted muscle growth, which are typically associated with traditional GH therapies (2)
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A systematic review of 76 different clinical trials looking at the risk of gallbladder disease for people taking GLP-1 agonists showed that there was an increase in risk for the development of gallbladder disease when taken at higher doses for long periods of time
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