Similarly, in the von Frey test, mice injected with the intraplantar vehicle after CFA induction displayed prolonged mechanical allodynia, which was significantly reversed by a single intraplantar administration of 5 or 10 g of exendin 939 (Fig
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furthermore, GLP-1 has been shown to promote HIF-1 translation via induction of mTOR in mouse islets 16
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Weeks 2-4: Significant improvements in tissue repair, pain reduction, and functional recovery
cardiovascular safety concerns related to TMAO generation remain under active investigation