( F ) GSEA recognized different gene sets in the high SLC25A39 expression group
GLP-1 maintenance may be helpful for individuals who have reached their goal weight, are concerned about weight regain, or want a structured plan when tapering off medication
Because the study was retrospective in nature, it couldn't prove that GLP-1 discontinuation caused any excess in pregnancy risks, only find associations
The theory is that people with these gene variants are less able to absorb folate, so taking methylfolate may be an effective option
In comparison, there were five patients with diabetes without gastroparesis amongst the GLP-1RA users (Table 1)
Around six or seven in every 1,000 people taking GLP-1 medications experienced hair loss each year, according to data cited in the study paper