Proc Natl Acad Sci (2019) 116:2350511
Key Research Applications Telomere elongation: Epitalon activates telomerase reverse transcriptase (hTERT), enabling DNA telomere elongation in human somatic cells and counteracting the Hayflick limit of replicative senescence
Survodutide Dosing# In the Phase 2 obesity trial, survodutide was administered as once-weekly subcutaneous injections at doses of 0.6 mg, 2.4 mg, 3.6 mg, and 4.8 mg
The drug is currently progressing through Phase 3 clinical trials under the TRIUMPH programme, which is evaluating its efficacy and safety across a range of populations
Patients should be trained on proper disposal of used needles in a sharps container and should never reuse needles due to infection risk and potential for needle damage that could cause pain or tissue trauma
Its important to regularly check how well the treatment is working and if its safe