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doi: 10.1002/dmrr.70081 Summary Keywords cardiomyopathy, diabetes, endothelium, HMGB1, inflammation, meta-analysis, rodent models, systematic review Citation Ranasinghe R, Mathai M and Zulli A (2026) Investigating the biomarkers of diabetic-cardiomyopathy with the high mobility group box-1 as a potential anti-inflammatory therapeutic target: Systematic Review and meta-analysis

Canli O, Alankus YB, Grootjans S, Vegi N, Hultner L, Hoppe PS, Schroeder T, Vandenabeele P, Bornkamm GW, Greten FR

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In the OASIS 4 clinical trial, patients achieved an average 16.6% body-weight reduction , with about one-third losing more than 20%