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rare but serious reactions include allergic responses

If you are still feeling persistently hungry at this dose, it is less likely to be a tolerance issue and more likely related to external factors: meal composition, eating speed, hydration, or sleep quality

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On the other hand, changes in the vaginal microbiome or vaginal pH during weight loss could make it easier for yeast to overgrow if protective bacteria are disrupted, according to Dr

For instance, in January 2025, the FDA approved semaglutide (Ozempic) as a medication to reduce the risk of kidney failure, kidney disease progression, and cardiovascular death in adults with type 2 diabetes and chronic kidney disease (CKD)

These symptoms generally subside as the body adjusts to the medication