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The FDA approved GLP-1s after testing them in large clinical trials (such as STEP and SURMOUNT ) at specific doses and intervals

This raises questions about cost-effectiveness and access, but if priced reasonably or if generics eventually become available, we may see a broad shift where anti-obesity pharmacotherapy (especially GLP-1/GIP-based) is as commonplace as antihypertensive or lipid-lowering therapy

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Nutrient deficiencies: Because the drugs suppress appetite and reduce caloric intake, some people may not get sufficient amounts of essential vitamins and minerals

For many people, tablets feel less intimidating and more familiar than self-injecting medication