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7.3 Development of combined intervention strategies The revised section now discusses the potential of combined therapeutic approaches, such as the co-administration of natural bioactive compounds with probiotics or prebiotics, to synergistically regulate gut microbiota composition, restore intestinal barrier integrity, and reduce hepatic oxidative stress and inflammation
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These shots bypass the digestive system, allowing for faster and more effective absorption of nutrients
158 MRP4 and MRP5 facilitate the efflux of cyclophosphamide and 5-fluorouracil and are transcriptionally regulated by Nrf2 signaling and therapeutic stress
Adjustments in timing or dosing may be necessary to optimize therapeutic outcomes
