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10.1159/000338048 91 KrnerS.HendricksM.KolleweK.ZapfA.DenglerR.SilaniV.et al
Exercise mimetics aim to reproduce selected biological effects of physical activity by pharmacologically engaging signaling pathways that are activated during exercise
Mice were euthanized on the last day of treatment
Attia believes that you can prevent declineor, as he puts it, square the longevity curvethrough an aggressive combination of exercise, lifestyle (nutrition, sleep, etc.), and elements from personalized health care, or what he calls Medicine 3.0
While the full mechanism isnt fully mapped out including how its produced or exactly where in the brain it acts the research suggests interesting links to sleep, recovery, hormone release and stress adaptation
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