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In conclusion, this trial demonstrates the superiority of oral semaglutide vs sitagliptin in reducing HbA 1c and body weight from baseline in a predominantly Chinese population with type 2 diabetes, as well as a safety and tolerability profile for semaglutide that is consistent with that of the GLP-1RA class
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GLP-1 Medications Fight Weight With Biology GLP-1s are different from older classes of prescription weight loss medications (like phentermine) because they work on key underlying metabolic pathways to support sustained weight loss
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Emerging 2025 research suggests semaglutide (the drug in Ozempic and Wegovy) is associated with lower RA disease activity, less pain, and improved joint outcomes especially in patients who also carry excess weight
Patients should also be asked if they felt self-disgust, depression, or guilt after these episodes
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