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The number of clusters (k=5) was chosen objectively by maximizing a combined score of: Silhouette coefficient on a discovery split: measures how well-separated the clusters are internally Adjusted Rand Index (ARI) on a held-out validation split: measures whether an independent reclustering of new data produces the same structure This two-stage validation approach guards against over-fitting the cluster count to a single sample

AST, 97.9 19.5) (Ahmad et al., 2016)

doi: 10.3760/cma.j.issn.0366-6999.2012.08.018 99 ZhuTWuXLZhangWXiaoM

But GLP-1 receptor agonists now offer the potential to profoundly transform obesity care

00:07:11 Vickie Danaher When thinking about meds for weight loss for our patients, we also want to tailor the selection based on things like cost and access, the patients other comorbidities, and other medication benefits

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