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It is possible that the effects are additive, that they are redundant, or that combining approaches produces unexpected outcomes

Campbell M, Fitzpatrick R, Haines A, Kinmonth AL, Sandercock P, Spiegelhalter D, et al

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The sensitivity analysis highlighted key cost-effectiveness drivers, such as medication costs and the BMI reduction effects of subcutaneous tirzepatide and oral semaglutide on the ICER