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For example, alcohol, high-fat and greasy foods, spicy foods, highly processed foodsand even certain vegetablescan trigger digestive issues, making it harder for the body to adapt to the medication

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Pro-oxidant shift in glutathione redox state during aging

facilitating the removal of short and medium chain fatty acid that accumulate during metabolism

In the STEP-4 withdrawal trial (N=803), participants who switched from semaglutide to placebo regained roughly two-thirds of their lost weight over 52 weeks ([8])