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Dietary considerations include: Regular, small meals Even with reduced appetite, maintaining consistent blood glucose levels helps prevent headaches related to low blood sugar Adequate protein intake Supports metabolic function during weight loss Monitoring caffeine consumption Maintaining usual caffeine intake prevents withdrawal headaches

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In addition, IGF-1 LR3 may promote fat breakdown by activating the MAPK pathway, leading to increased levels of free fatty acids and further exacerbating insulin resistance, forming a vicious cycle