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The fat that provides the volume and naturally youthful contours to the face decreases significantly, which can make aesthetic changes such as: Loose or Sagging Skin After you lose a bunch of weight, unfortunately your skin may be stretched out too far and unable to fully retract to smoothly cover your smaller body

La introduccin de la semaglutida , una molcula ms resistente a la DPP-4 y de dosificacin semanal, y la tirzepatida , un coagonista de GLP-1 , permite ahora una reduccin de peso del 15% al 20% o ms en personas con obesidad o sobrepeso con complicaciones mdicas

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