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Diagnosis is made with the presence of HLA-B27 antigens, the presence of bilateral sacroiliitis, and ocular examination to assess for uveitis
SCM was established by group of experts who have more than ten years experiences in pharmaceutical and food ingredients industries
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Evaluation: Body fat (DXA scanning) Lean mass Insulin sensitivity Energy expenditure What they found: The combination showed an additive effect on fat reduction vs monotherapy AOD-9604 partially protected lean mass during GLP-1-induced weight reduction Increased energy expenditure in combination (~3 % vs GLP-1 alone) No new safety signals Why it matters: It validates the concept of combination , the idea that AOD-9604 may not work on its own, but can add value in combination with incretin agonists
Researchers studying the protective factors in the stomach in the early 1990s named the parent molecule Body Protection Compound, abbreviated BPC
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