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GLP-1 receptor agonists for major cardiovascular and kidney outcomes in type 1 diabetes
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The mechanisms underlying hair loss during GLP-1 therapy likely involve multiple contributing factors rather than a single direct drug effect
335,336 The expression of iNOS is primarily activated by the NF-B pathway, which is activated and translocated to the nucleus upon inflammatory stimulation (such as bacterial endotoxins or pro-inflammatory cytokines), thus increasing the transcription and expression of iNOS