These require patients to use an insulin syringe to give themselves an injection weekly
Adverse event management may require patience given the gradual elimination of the medication
For people with existing cardiac conditions, this needs monitoring
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Additionally, voriconazole is also a substrate and inhibitor of CYP2C19, and glucocorticoids (CYP2C19 inducers) and CYP2C19 gene polymorphisms can influence its metabolism (Tian et al., 2021)
Statistical analysis was performed by t -test (unpaired or paired, as indicated), one-way analysis of variance (ANOVA), two-way ANOVA (time treatment or genotype treatment) with post hoc comparisons (where appropriate, as indicated in the figure legends)