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Structured monitoring is a key component of assessing whether retatrutide is producing the desired therapeutic effect
Similar content being viewed by others Log in or create a free account to read this content Gain free access to this article, as well as selected content from this journal and more on nature.com or Abbreviations COX: cytochrome c oxidase CS: citrate synthase CTNS: cystinosin GSH: glutathione GSSG: oxidized glutathione NC: nephropathic cystinosis PG: pyroglutamic acid References Gahl WA, Bashan N, Tietze F, Bernardini I, Schulman JD 1982 Cystine transport is defective in isolated leukocyte lysosomes from patients with cystinosis
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The real-world data showing that 77% of people maintain at least some weight loss after stopping GLP-1 medications suggests that lasting behavioral change is possible
GLP-1 also acts as a satiety signal by activating receptors on vagal afferent neurons that transmit signals from the gut to the hypothalamic satiety centers, including regions that regulate appetite, energy expenditure, and food reward
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