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(2018) 50(2):e12840
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Commercial Development: In August 2025, Jocasta Neuroscience raised $35 million in Series A funding to advance JN-0413, a proprietary -klotho formulation, through Phase 1 trials with IND submission planned for Q4 2026
This dual effect on both sides of the energy balance equation is why retatrutide produced the highest weight loss percentages of any single-agent trial
Volante et al., 2003
Because of this, their sourcing is easier to evaluate
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