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In the Phase 2 trial, participants on the higher doses showed 82-86% reduction in liver fat at 48 weeks

USP8 deubiquitinates and stabilizes ITCH, and forms a USP8-ITCH complex, which then mediates the ubiquitination and subsequent proteasomal degradation of cellular FLICE - like inhibitory protein (c-FLIP), ultimately promoting caspase-8-mediated apoptosis in cancer cells [71]

Some ingredients shouldnt be taken too frequently

Presented for research literature review only Thompson CH et al

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