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Injectable peptides from licensed compounding pharmacies are sterile and properly dosed

For example, people with digestive issues may not absorb liquid, gummy, or pill forms of vitamin B12 effectively

Etiology Genetics COL5A1 or COL5A2 mutation in 40-50% less common mutations identified below Associated conditions Connective tissue disorder characterized by hyperelastic/fragile skin joint hypermobility and dislocation generalized ligamentous laxity poor wound healing early onset arthritis additional features Classification Berlin Classification (1988) - revised Types I - XI exist Types II and III - most common and least disabling Villefranche Classification (1998) Presentation Symptoms double-jointedness easily damaged, bruised, & stretchy skin easy scarring & poor wound healing increased joint mobility, joint popping, early arthritis especially shoulders, patellae, ankles chronic musculoskeletal pain (50%) Physical exam a score of 5 or more on 9-point Beighton-Horan scale defines joint hypermobility

A full blood count and serum B12 measurement are straightforward investigations that can help differentiate causes

Improved circulation and reduced inflammation also suggest benefits for the gut-brain axi, possibly easing brain fog, mood swings, and cognitive fatigue that plague so many patients

I note the carboxyhaemoglobin level is slightly raised