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All donors gave written informed consent and protocols were approved by the ethical review board of Fundao Hospitalar de Hematologia e Hemoterapia do Amazonas (CAEE: 51257921.2.0000.0009, approval number #4.982.395/2021)

3A, B), indicating more severe renal function

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Vitamin B12 injections, typically hydroxocobalamin in the UK, are evidence-based therapies for confirmed B12 deficiency, treating conditions such as pernicious anaemia and malabsorption syndromes