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The GLP-1 agonists and multi-agonists dominate for raw weight loss effectiveness, with retatrutide and CagriSema potentially matching or exceeding tirzepatide

New users: start with half serving ( tablespoon) to assess thermogenic tolerance

Jean-Pierre Raufman was a freshly minted gastroenterologist when he arrived at the National Institutes of Health (NIH) in Bethesda, Maryland, in July 1980