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Leptin levels decrease dramatically with weight loss and often dont fully recover, leading to persistent hunger signals
It's not the drug, it's the weight loss
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Currently, the anti-obesity medications that have been approved by the FDA for chronic weight management are orlistat, phentermine/topiramate, naltrexone/bupropion, and liraglutide
A Certificate of Analysis is available for reference, providing information on identification, purity, and concentration
Clinicians also weigh benefits beyond weight, as long-term outcomes include cardiovascular effects
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