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Both are classified as Category 2 (significant safety risks)

It is often discussed in sleep and circadian rhythm contexts, especially where age-related sleep dysregulation affects recovery and resilience

Pharmacol Res 187:106631

Together they work on melanin production, help reduce existing tan, fade dark patches and acne marks, and support a brighter and more even complexion on face and body

Fixed-dose combination means less flexibility in dosing

It is not a dietary supplement, medical food, cosmetic, or drug, and it has not been evaluated by the Food and Drug Administration (FDA) for therapeutic or diagnostic application