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Clinicians should recognize that patients undergoing polypharmacy require heightened vigilance, comprehensive monitoring, and specialized counseling

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When semaglutide patients switch to tirzepatide In the graph below, you can see that patients who switched from semaglutide to tirzepatide, either because of greater side effects on semaglutide or because they felt they hit a plateau on semaglutide, they continued to lose weight on tirzepatide