10.1016/j.bcp.2015.11.027 138 ZhouH
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Deviations shorten shelf life and can reduce efficacy or safety
Initially, many patients notice a significant reduction in hunger and a greater sense of fullness within the first few weeks as the dose is gradually increased
Severe gastroparesis or significant gastrointestinal motility disorders also warrant avoidance as GLP 1 induced gastric emptying delays can worsen existing symptoms
It can cause some side effects including stomach upset, nausea, vomiting, dry mouth, headache, and restlessness