An analysis by Elsaid et al
These effects are hypothesized to stem from classical growth factor mechanisms, involving increased gene expression linked to cell growth, repair, and replacement, along with an elevation in cellular metabolism
Conversely, symptoms suggesting excessive thyroid hormone replacement (hyperthyroidism), including palpitations, tremor, anxiety, heat intolerance, or insomnia, particularly in the context of significant weight loss, warrant evaluation and possible levothyroxine dose reduction
Alternative 1 mg and 2 mg starting points For people with prior GLP-1 agonist experience, starting at 1 mg or 2 mg is reasonable and well-supported by clinical data
Different patients have different comorbidities, GI tolerance, exercise limitations, nutritional risk, and treatment goals
Ist GLP-1 Insulin