Portion control becomes essential as appetite decreases on GLP-1 therapy
One major uncertainty is how nanoparticles behave and persist in the human body
BUT - this doesnt mean that supporting your bodys production of GLP-1 hormone is a bad idea
264,265,266 The hypothalamus contains various neurons that respond to different nutritional signals and hormones, like GLP-1, to regulate food intake
Clinical trial data for tirzepatide, including the SURMOUNT and SURPASS programmes, have primarily focused on glycaemic control, weight reduction, and cardiovascular outcomes
They found that intestinal flora may mediate the release of the intestinal hormone GLP-1 through the short-chain fatty acid (SCFA)-GPCR pathway, thereby increasing satiety and slowing gastric emptying, ultimately reducing obesity