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This is because, in animal studies, higher doses of semaglutide were found to increase the risk of developing thyroid C-cell tumors
Missing data were imputed using available data according to value and timing of last available observation on treatment and endpoints baseline value from retrieved subjects (RD-MI)
A genome-wide CRISPRCas9 knockout screen identifies FSP1 as the warfarin-resistant vitamin K reductase
Dda Ildik Forrs:
Supplementary findings also showed higher reduction in fasting insulin levels in the semaglutide group (7% vs 26%) and higher reductions in liver function biomarkers (ALT and AST reduction of 11% vs 24% respectively) - however this analysis was performed only in a small subset of patients (n=95 in the intervention and n=45 in placebo group)
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