Nevertheless, excessive loss of functional muscle remains a legitimate concern, particularly in: Adults over age 50 Patients beginning with low muscle mass Postmenopausal women Patients consuming very little protein People who do not perform resistance exercise Patients losing weight very rapidly People with chronic illness, physical limitations, or prolonged inactivity Patients who repeatedly increase medication despite inadequate nutrition The goal is therefore not to prevent every change in measured lean mass
Pigs, goats, sheep, dogs, cats: 1mL per 10-15 kg of body weight
For GLP-1 patients, that matters because rapid weight loss often leaves skin looking dehydrated and fragile before volume loss becomes severe
In addition, dopamine transporter availability was lower in the exenatide group compared with the placebo group
In that sense, B12 injections can support the conditions that make weight loss easier to maintain
Hoffer, M