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[28] [29] This pharmacovigilance system enables ongoing safety monitoring and rapid identification of potential safety signals
So far, however, B cell-directed agents have not been tested in the early disease stage, precluding conclusions regarding the usefulness of such interventions in delaying or even preventing progression to later stages
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doi: 10.1016/j.neuropharm.2019.107668 105 SiddiquiNAliJParvezSZameerSNajmiAKAkhtarM
10.1016/S0140-6736(84)92209-8 Stumpf DA, Parker WD, Haas R: Carnitine deficiency with valproate therapy
Published studies show that choline supports VLDL assembly and prevents hepatic steatosis, inositol improves insulin sensitivity in PCOS models, methionine provides methyl groups for hepatic detoxification, and B12 supports energy metabolism
