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Some start weekly for a short period, then move to every two to four weeks

Alongside vaccination, good hygiene practices can help limit exposure

The gel is reapplied at regular intervals over 30-60 minutes for maximum effectiveness

The demyelination is thought to result from the increase in methylmalonyl-CoA that results from vitamin B12 deficiency that is associated with loss of methylmalonyl-CoA mutase activity

Food and Drug Administration (FDA) warned companies who sold over-the-counter (OTC) chelation products and stated that such "products are unapproved drugs and devices and that it is a violation of federal law to make unproven claims about these products