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Development of potent H 2 O 2 -decomposing enhancers for Hb pseudoperoxidase activity Although HTPEB enhances the peroxidase-like activity of Hb, its poor BBB permeability and solubility in aqueous solutions limit its therapeutic potential (Supplementary Table 1)

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448 AAP peptides possess recognition and membrane-targeting functions, facilitating gene delivery through interactions with DNA and siRNA

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Drug rechallenge and treatment beyond progressionimplications for drug resistance

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We present some clinical trials of IR intervention in Table 2

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Support for maintaining adequate energy-yielding metabolism: Thanks to vitamin B6

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