LauzierDCJayaramanKYuanJYDiwanDVellimanaAKOsbunJWet al
For ankle injuries specifically, subcutaneous injection near the affected area at 0.25 to 0.50 mg daily for 4 to 8 weeks represents the most common protocol among researchers and biohackers
However, no human pharmacokinetic study has measured plasma levels after oral dosing
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Ceramide levels in blood plasma correlate with major depressive disorder severity and its neutralization abrogates depressive behavior in mice