Patients with recurrent depression exhibit reduced hippocampal volume and hippocampal atrophy in the brain when compared to healthy controls ( Figure 2 ) (Sheline et al., 1999)
Questi risultati posizionano Retatrutide come il farmaco pi efficace mai sviluppato per lobesit, avvicinandosi ai risultati ottenibili con la chirurgia bariatrica
Emerging evidence suggests that, beyond their metabolic efficacy, GLP-1 RAs influence a range of psychological processesincluding reward responsivity, impulse control, emotional regulation, and treatment adherencewhich may be particularly relevant for individuals with binge-type eating behaviors or psychiatric comorbidities
The other remains fully within the Lilly pipeline as potentially the most powerful weight loss compound ever tested in humans
Lower GLP-1 means increased hunger and weight regain
This eventually leads to reduced portion sizes, fewer cravings and mindfulness when eating, allowing the individual to be in a caloric deficit in a sustainable manner