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While some studies have shown a correlation between computational results on mTYR and experimental results on human tyrosinase (hTYR) 8 , the lack of a resolved hTYR crystal structure has hindered a deeper understanding of the inhibitory mechanisms of many compounds against hTYR

Standard oral formulations achieve only 0.7% bioavailability, limiting blood level increases compared to IV delivery

Antitumor activity of liposomal encapsulated tiazofurin and its NAD-analogue [PMID: 3181990] Laboratory literature summary: Antitumor activity of liposomal encapsulated tiazofurin and its NAD-analogue