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In Phase 2 clinical research, retatrutide demonstrated body weight reductions of up to 24.2% over 48 weeks, the largest reported for any incretin-based compound at that stage of development [8]

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Patients may experience side effects such as gastrointestinal discomfort, and certain populations, such as those with pancreatitis or severe gastrointestinal disorders, may not be suitable candidates

A specific half-life value in hours is not consistently published in open-access pharmacokinetic summaries

The application can usually be performed in 6 sessions and 1 or 2 times a week

According to a statement from the company, revenue increased 45% to $13.53 billion, driven by volume growth from Mounjaro and Zepbound. At the same time, lawsuits related to injuries caused by Mounjaro and other GLP-1 drugs also increased