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Its inclusion addresses the abdominal discomfort and irregularity dimension of GLP-1 GI side effects, based on the ingredient-level evidence described above
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GLP-1 medications affect gastric motility, and some people experience nausea, changes in bowel habits, or other GI symptoms during treatment particularly in the early months
Tirzepatide's dual action (activating both GIPR pathways) explains its edge over semaglutide in clinical trials, with patients achieving 20-25% weight loss versus 12-18%
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