When a recently-eaten meal reaches cells in the intestine, they release a glucagon-like peptide 1, or GLP-1
Most patients begin to notice weight loss within 12 to 16 weeks, with more significant results occurring over the following months
Adherence to your doctors dosage and administration instructions is crucial for optimal results
has divulged incretin analogues acting as dual agonists of gastric inhibitory polypeptide (GIPR) receptor/GLP-1 or GLP-1/glucagon receptor (GCGR) or triple agonists of GIPR/GLP-1/GCGR reported to be useful for the treatment of type 2 diabetes, dyslipidemia, obesity, metabolic syndrome, neurodegeneration, fibrosis and cardiovascular disorders
Key Differences Semaglutide: GLP-1 only
These data were first presented by Amanda Johnson, MD, Mayo Clinic, Rochester, Minnesota, at the 2026 Crohns and Colitis Congress on Friday, January 23, 2026, in Las Vegas, Nevada