10.1016/j.pharmthera.2013.12.014 Pharmacol
Lab results confirming B12 deficiency, or a physician-confirmed diagnosis of pernicious anemia, must be on file before the injection is administered
For individuals requiring supplementation due to confirmed deficiency or malabsorption, therapeutic doses vary considerably depending on the underlying cause: Dietary deficiency : 50150 micrograms daily orally, or cyanocobalamin tablets as prescribed Pernicious anaemia : Initially hydroxocobalamin 1 mg intramuscularly three times weekly for two weeks, then maintenance injections every two to three months [3] Neurological involvement : More intensive regimens may be required, with hydroxocobalamin injections on alternate days until symptom improvement [3] NICE guidance emphasises that supplementation should be evidence-based rather than speculative
In some cases, dogs on BPC-157 may be able to reduce their NSAID dose over time but dont make that change without your vets input
Let me know if you need further adjustments
It suppresses RNA production in 70% of 54 human genes overexpressed in cancer patients and upregulates 10 caspase and caspase-associated genes, which are crucial for programmed cell death (apoptosis) a key defense against cancer
