Hall KD
In a study on young, healthy, physically active adults, 1,500 mg of Nitrosigine enhanced flow-mediated dilation (FMD) nearly as much as 8,000 mg of Citrulline Malate 2:1 (~5,333 mg of L-Citrulline), demonstrating that Nitrosigine is one of the most potent and compact capsule-sized nitric oxide enhancers available [R, R, R, R]
So far preferential activation of GIPR activation, combined with less activation of GLP1R and even less activation of GR appear to have produced the most effective combination, as shown by Retatrutide, although whether this mixture is indeed the optimal is still an open question
Estimated Levels, a pharmacokinetic curve showing your dose building, peaking, and tapering across the cycle, based on FDA prescribing information for established medications and Phase 3 clinical trial data for newer molecules
[1] Cellular Energy Production - Glutathione protects mitochondria (the cell's power plants) from oxidative damage, potentially supporting more efficient energy production during exercise
How long does it take for GLP-1s to work